Screening and
Follow-Up Tests
All study participants undergo rigorous screening tests. These include biomarkers related to infectious diseases, metabolic health, blood values (including the complete blood count), hormones, inflammation, kidney function, and liver function.
Biomarkers
The Advanced Panel is included in both Baseline and Follow-Up tests.
Baseline
Infectious Diseases
HbsAg (Hepatitis B)
HIV I & II
Syphilis VDRL
Anti HCV (Hepatitis C)
Metabolic
Albumin
ALP
ALT
AST
Potassium
Sodium
Lipid Profile
Total Cholesterol
LDL-Cholesterol
HDL-Cholesterol
Triglycerides
APO A
APO B
Blood Values and Complete Blood Count
HbA1c
Homocysteine
Glucose
Ferritin
CBC
Hormones
Testosterone (male)
TSH (female)
Inflammation
High-sensitive CRP
ESR
Kidney
Creatinine
Liver
Total Bilirubin
Follow-Up
Lipid Profile
Total Cholesterol
LDL-Cholesterol
HDL-Cholesterol
Triglycerides
APO A
APO B
Blood Values and Complete Blood Count
HbA1c
Homocysteine
Glucose
Ferritin
CBC
Hormones
Testosterone (male)
TSH (female)
Inflammation
High-sensitive CRP
ESR
Kidney
Creatinine
Liver
Total Bilirubin
Advanced Panel
Cytokines and Chemokines
Eotaxin
IL-1 RA
IL-1b
IL-2
IL-4
IL-6
IL-7
IL-10
IL-12 p70
IL-13
IL-15
IL-17A
MIP-1A
MIP-1b
IFN-g
MCP-1
GM-CSF
IP-10
TGF-a
TNF-a
TNF-b
VEGF A
Aging
Telomere Length
Total Telomere length (kb)
Average length per telomere end (kb)
DNA Methylation
Total Methylation (5-mC%/total DNA)
5-mC%/cytosine content
Histone 3 Modification
Histone H3K4 methylation (%)
Immunoprofiling
Innate Immune Cells
Total (CD3-CD56+) NK cells %
Mature (CD16+CD56+) NK cells %
Immature (CD16-CD56-) NK cells %
Total monocytes (CD3-CD19-CD14+) %
Classical (CD14hiCD16-) monocytes %
Intermediate (CD14+CD16+) monocytes %
Non-classical (CD16hiCD14+) monocytes %
Adaptive Immune Cells
CD4+ (CD3+CD19-) helper T cells %
Naive (CD45RA+CD27+) CD4+ helper T cells %
Central memory (CD45RA-CD27+) CD4+ helper T cells %
Effector (CD45RA-CD27-) CD4+ helper T cells %
EMRA (CD45RA+CD27-) CD4+ helper T cells %
CXCR3+ CD4+ helper T cells %
Regulatory T cells (CD25+ FOXP3+) %
Activated regulatory T cells (CD25hiFOPX3hi)
CD8+ (CD3+CD19-) cytotoxic T cells %
Naive (CD45RA+CD27+) CD8+ cytotoxic T cells %
Central memory (CD45RA-CD27+) CD8+ T cells %
Effector memory (CD45RA-CD27-) CD8+ cytotoxic T cells %
EMRA (CD45RA+CD27-) CD8+ cytotoxic T cells %
CD19+ B cells %
Naive (IgD+CD27-) B cells %
Immature transitional (CD5+CD38+) B cells %
IgD+ memory (IgD+CD27+) B cells %
Class-switched Memory (IgD-CD27+) B cells %
Total memory (CD27+) B cells %
Plasmablast (CD27+CD38+) %
BAFFR+ B cells %
Regulatory B cells %
Infectious Diseases
- HbsAg (Hepatitis B)
- HIV I & II
- Syphilis VDRL
- Anti HCV (Hepatitis C)
Metabolic
- Albumin
- ALP
- ALT
- AST
- Potassium
- Sodium
Lipid Profile
- Total Cholesterol
- LDL-Cholesterol
- HDL-Cholesterol
- Triglycerides
- APO A
- APO B
Blood Values and Complete Blood Count
HbA1c
Homocysteine
Glucose
Ferritin
CBC
Hormones
Testosterone (male)
TSH (female)
Inflammation
High-sensitive CRP
ESR
Kidney
Creatinine
Liver
Total Bilirubin
Lipid Profile
Total Cholesterol
LDL-Cholesterol
HDL-Cholesterol
Triglycerides
APO A
APO B
Blood Values and Complete Blood Count
HbA1c
Homocysteine
Glucose
Ferritin
CBC
Hormones
Testosterone (male)
TSH (female)
Inflammation
High-sensitive CRP
ESR
Kidney
Creatinine
Liver
Total Bilirubin
Cytokines and Chemokines
Eotaxin
IL-1 RA
IL-1b
IL-2
IL-4
IL-6
IL-7
IL-10
IL-12 p70
IL-13
IL-15
IL-17A
MIP-1A
MIP-1b
IFN-g
MCP-1
GM-CSF
IP-10
TGF-a
TNF-a
TNF-b
VEGF A
Aging
Telomere Length
Total Telomere length (kb)
Average length per telomere end (kb)
DNA Methylation
Total Methylation (5-mC%/total DNA)
5-mC%/cytosine content
Histone 3 Modification
Histone H3K4 methylation (%)
Immunoprofiling
Innate Immune Cells
Total (CD3-CD56+) NK cells %
Mature (CD16+CD56+) NK cells %
Immature (CD16-CD56-) NK cells %
Total monocytes (CD3-CD19-CD14+) %
Classical (CD14hiCD16-) monocytes %
Intermediate (CD14+CD16+) monocytes %
Non-classical (CD16hiCD14+) monocytes %
Adaptive Immune Cells
CD4+ (CD3+CD19-) helper T cells %
Naive (CD45RA+CD27+) CD4+ helper T cells %
Central memory (CD45RA-CD27+) CD4+ helper T cells %
Effector (CD45RA-CD27-) CD4+ helper T cells %
EMRA (CD45RA+CD27-) CD4+ helper T cells %
CXCR3+ CD4+ helper T cells %
Regulatory T cells (CD25+ FOXP3+) %
Activated regulatory T cells (CD25hiFOPX3hi)
CD8+ (CD3+CD19-) cytotoxic T cells %
Naive (CD45RA+CD27+) CD8+ cytotoxic T cells %
Central memory (CD45RA-CD27+) CD8+ T cells %
Effector memory (CD45RA-CD27-) CD8+ cytotoxic T cells %
EMRA (CD45RA+CD27-) CD8+ cytotoxic T cells %
CD19+ B cells %
Naive (IgD+CD27-) B cells %
Immature transitional (CD5+CD38+) B cells %
IgD+ memory (IgD+CD27+) B cells %
Class-switched Memory (IgD-CD27+) B cells %
Total memory (CD27+) B cells %
Plasmablast (CD27+CD38+) %
BAFFR+ B cells %
Regulatory B cells %